Structure of PDB 5akm Chain F Binding Site BS03

Receptor Information
>5akm Chain F (length=174) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVSGISAYLLGLIISDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPL
MQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMRE
QIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDD
HRHGVYVLNISLRDRIKFVHTILS
Ligand information
Receptor-Ligand Complex Structure
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PDB5akm Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
N32 R33 S34 E35 Y36 R37 S67 K68 Q70 R81 S83 K85 E117 W128 N129 K130 H158 V160
Binding residue
(residue number reindexed from 1)
N27 R28 S29 E30 Y31 R32 S62 K63 Q65 R76 S78 K80 E112 W123 N124 K125 H153 V155
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function

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Biological Process
External links
PDB RCSB:5akm, PDBe:5akm, PDBj:5akm
PDBsum5akm
PubMed26045557
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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