Structure of PDB 4ztt Chain F Binding Site BS03

Receptor Information
>4ztt Chain F (length=164) Species: 536056 (Escherichia coli DH1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHLKPEMIEKLNEQMNLELYASLLYQQMSAWCSYHTFEGAAAFLRRHAQE
EMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQ
KINELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGE
GLYFIDKELSTLDT
Ligand information
Ligand IDO
InChIInChI=1S/H2O/h1H2
InChIKeyXLYOFNOQVPJJNP-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		O
CACTVS 3.341[O]
FormulaO
NameOXYGEN ATOM
ChEMBLCHEMBL1098659
DrugBankDB09145
ZINC
PDB chain4ztt Chain F Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ztt Structural Basis of Novel Iron-Uptake Route and Reaction Intermediates in Ferritins from Gram-Negative Bacteria.
Resolution1.83 Å
Binding residue
(original residue number in PDB)		E50 H53 E94
Binding residue
(residue number reindexed from 1)		E51 H54 E95
Annotation score1
Enzymatic activity
Enzyme Commision number 1.16.3.2: bacterial non-heme ferritin.
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0016491 oxidoreductase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0140315 iron ion sequestering activity
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0006974 DNA damage response
GO:0006979 response to oxidative stress
GO:0071281 cellular response to iron ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ztt, PDBe:4ztt, PDBj:4ztt
PDBsum4ztt
PubMed27777002
UniProtP0A998|FTNA_ECOLI Bacterial non-heme ferritin (Gene Name=ftnA)

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