Structure of PDB 4xln Chain F Binding Site BS03

Receptor Information
>4xln Chain F (length=347) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSDPVRQYLHEIGQVPLLTLEEEIDLARKVEEGMEAIKKLSEATGLDQEL
IREVVRAKILGTARIQKIPGLKEKPDPKTVEEVDGKLKSLPKELKRYLHI
AREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEK
FEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTAR
QLQQELGREPSYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKD
SFYGDFIPDENLPSPVEAAAQSLLSEELEKALSKLSEREAMVLKLRKGLI
DGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLE
Ligand information
Receptor-Ligand Complex Structure
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PDB4xln Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
D338 E339
Binding residue
(residue number reindexed from 1)
D247 E248
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4xln, PDBe:4xln, PDBj:4xln
PDBsum4xln
PubMed26349032
UniProtQ9EZJ8|SIGA_THEAQ RNA polymerase sigma factor SigA (Gene Name=sigA)

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