Structure of PDB 3qrf Chain F Binding Site BS03

Receptor Information
>3qrf Chain F (length=82) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAI
RHNLSLHKCFVRVESEKGAVWTVDELEFRKKR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3qrf Chain F Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3qrf Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		L389 S390 H392 F395
Binding residue
(residue number reindexed from 1)		L54 S55 H57 F60
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3qrf, PDBe:3qrf, PDBj:3qrf
PDBsum3qrf
PubMed21458306
UniProtQ9BZS1|FOXP3_HUMAN Forkhead box protein P3 (Gene Name=FOXP3)

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