Structure of PDB 3mkv Chain F Binding Site BS03

Receptor Information
>3mkv Chain F (length=413) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTFLFRNGALLDPDHPDLLQGFEILIEDGFIREVSDKPIKSSNAHVIDVK
GKTIMPGLIDLHVHVVAIEFNLPRVATLPNVLVTLRAVPIMRAMLRRGFT
TVRDAGGAGYPFKQAVESGLVEGPRLFVSGRALSQTGGHADPRARSDYMP
PDSPCGCCVRVGALGRVADGVDEVRRAVREELQMGADQIKIMASGGVASP
TDPVGVFGYSEDEIRAIVAEAQGRGTYVLAHAYTPAAIARAVRCGVRTIE
HGNLIDDETARLVAEHGAYVVPTLVTYDALASEGEKYGLPPESIAKIADV
HGAGLHSIEIMKRAGVKMGFGTDLLGEAQRLQSDEFRILAEVLSPAEVIA
SATIVSAEVLGMQDKLGRIVPGAHADVLVVDGNPLKSVDCLLGQGEHIPL
VMKDGRLFVNELE
Ligand information
Ligand IDCO3
InChIInChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
InChIKeyBVKZGUZCCUSVTD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=O)([O-])[O-]
ACDLabs 10.04
CACTVS 3.341		[O-]C([O-])=O
FormulaC O3
NameCARBONATE ION
ChEMBL
DrugBankDB14531
ZINC
PDB chain3mkv Chain F Residue 427 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3mkv Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily .
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H140 V198 A199 Y234
Binding residue
(residue number reindexed from 1)		H139 V197 A198 Y233
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3mkv, PDBe:3mkv, PDBj:3mkv
PDBsum3mkv
PubMed20604542
UniProtB2T4I1

[Back to BioLiP]