Structure of PDB 1ev6 Chain F Binding Site BS03

Receptor Information
>1ev6 Chain F (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>1ev6 Chain E (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1ev6 R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol
Resolution1.9 Å
Binding residue
(original residue number in PDB)
C7 L11 V18 C19 R22 G23 F24 Y26 T30
Binding residue
(residue number reindexed from 1)
C7 L11 V18 C19 R22 G23 F24 Y26 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1ev6, PDBe:1ev6, PDBj:1ev6
PDBsum1ev6
PubMed11092919
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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