Structure of PDB 8q9r Chain E Binding Site BS03

Receptor Information
>8q9r Chain E (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKG
Ligand information
Receptor-Ligand Complex Structure
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PDB8q9r Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		G2 R3 I6 K23 R24 K30
Binding residue
(residue number reindexed from 1)		G1 R2 I5 K22 R23 K29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8q9r, PDBe:8q9r, PDBj:8q9r
PDBsum8q9r
PubMed38492719
UniProtQ05BX2

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