Structure of PDB 8amu Chain E Binding Site BS03

Receptor Information
>8amu Chain E (length=131) Species: 1311 (Streptococcus agalactiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKEKARYFTFLLYPESIPSDWELKLETLGVPMAISPLHDKDKSSIKGQKY
KKAHYHVLYIAKNPVTADSVRKKIKLLLGEKSLAMVQVVLNVENMYLYLT
HESKDAIAKKKHVYDKADIKLINNFDIDRYV
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8amu Chain E Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8amu Structures of pMV158 replication initiator RepB with and without DNA reveal a flexible dual-function protein.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		H39 D42 H55 H57
Binding residue
(residue number reindexed from 1)		H38 D41 H54 H56
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005727 extrachromosomal circular DNA

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8amu, PDBe:8amu, PDBj:8amu
PDBsum8amu
PubMed36688326
UniProtP13921|REPB_STRAG Replication protein RepB (Gene Name=repB)

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