Structure of PDB 7txc Chain E Binding Site BS03

Receptor Information
>7txc Chain E (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRPFKCSVCEKTYKDPATLRQHEKTHWLTRPFPCNICGKMFTQRGTMTRH
MRSHLGLKPFACDECGMRFTRQYRLTEHMRVHSG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7txc Chain E Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7txc HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.
Resolution3.04 Å
Binding residue
(original residue number in PDB)		C535 C538 H551 H555
Binding residue
(residue number reindexed from 1)		C34 C37 H50 H54
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7txc, PDBe:7txc, PDBj:7txc
PDBsum7txc
PubMed35941187
UniProtQ96JB3|HIC2_HUMAN Hypermethylated in cancer 2 protein (Gene Name=HIC2)

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