Structure of PDB 7swl Chain E Binding Site BS03

Receptor Information
>7swl Chain E (length=480) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSILDIAGVDDTLQRLLKEVWFPLRGGEACEKMGYRYDNGVLLHGPSGCG
KTTLAHAIAGSIGVAFIPVSAPSVIGGTSGESEKNIRDVFDEAIRLAPCL
IFLDQIDAIAGRRESANKGMESRIVAEIMNGMDRIRQNTPLGKNVVVLAA
TNRPEFLDPAIRRRFSVEIDMGMPSERAREQILRSLTRDLINFKELAKMT
PGYVGSDLQYVVKAAVSESFQAKITMEQFRKAVSLVQPASTIPDTTWSHV
GALEDVRKKLEMSIIGPIKNPELFTRVGIKPAAGILLWGPPGCGKTLVAK
AVANESKANFISIKGPELLNKYVGESERAVRQLFSRAKSSAPCILFFDQM
DALVPRRDDSLSDASARVVNTLLTELDGVGDRSGIYVIGATNRPDMIDEA
IRRPGRLGTSIYVGLPSAEDRVKILKTLYRNTVTTDADLEKVALDLSGAD
LGNLMQAAAQACLERVITMEDWEKALNEVK
Ligand information
Ligand IDADP
InChIInChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyXTWYTFMLZFPYCI-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N
FormulaC10 H15 N5 O10 P2
NameADENOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL14830
DrugBankDB16833
ZINCZINC000012360703
PDB chain7swl Chain E Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7swl Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Resolution2.88 Å
Binding residue
(original residue number in PDB)		V503 G504 G545 C546 G547 T549 L550 I677 G733 A734
Binding residue
(residue number reindexed from 1)		V250 G251 G292 C293 G294 T296 L297 I424 G448 A449
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7swl, PDBe:7swl, PDBj:7swl
PDBsum7swl
PubMed36090660
UniProtG0RZG1

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