Structure of PDB 7mi4 Chain E Binding Site BS03

Receptor Information
>7mi4 Chain E (length=95) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEHLYIVSYDIRNQRRWRRLFKTMHGFGCWLQLSVFQCRLDRIRIIKMEA
AINEIVNHAEDHVLILDLGPAENVKPKVSSIGKTFDPILRQAVIV
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7mi4 Chain E Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7mi4 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Y9 D10 S34
Binding residue
(residue number reindexed from 1)		Y9 D10 S34
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7mi4, PDBe:7mi4, PDBj:7mi4
PDBsum7mi4
PubMed34588691
UniProtQ74H35|CAS2_GEOSL CRISPR-associated endoribonuclease Cas2 (Gene Name=cas2)

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