Structure of PDB 7eby Chain E Binding Site BS03

Receptor Information

>7eby Chain E (length=762) Species: 1744839 (Cupriavidus sp. P4-10-C)

PTDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQI
DLWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVA
EAFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTL
NFTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAA
LKKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSL
RYVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYE
TDPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHAD
DASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQ
VYADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAY
NPSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSS
LRDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRG
WDGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLA
VLEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIF
RHPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRM
VLDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVE
RAAEKRIELTPR

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 7eby Chain E Residue 906

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7eby Protein Engineering of d-Succinylase from Cupriavidus sp. for d-Amino Acid Synthesis and the Structural Implications.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): N165 E169 D354 E356 D357 G487
• Binding residue (residue number reindexed from 1): N151 E155 D292 E294 D295 G425
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Biological Process

• GO:0017000 antibiotic biosynthetic process

External links

• PDB: RCSB:7eby, PDBe:7eby, PDBj:7eby
• PDBsum: 7eby
• UniProt: A0A0N7KZ58