Structure of PDB 7bkc Chain E Binding Site BS03

Receptor Information
>7bkc Chain E (length=411) Species: 323259 (Methanospirillum hungatei JF-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAKGDMLYAWAKDAEIQKKGECGGAVTALLKHALETKMVDAVVAIKKGKD
LYDAVPTVITNPEDIIQTAGSLHCGTLLIPKLIKKYLNGAKDMKLAVTCK
GCDAMAFYELAKRNQINLDNIIMIGVNCGGSVSPVTARKMISNKFGVDPD
TVHKEEIDKGQFIIEYEGGHKGIKIDELEEEGYGRRSNCRRCKMKIPRQA
DIAAGNWGVIGDKAGKATFLEICSEKGANLVNSAQSKGALEISPADPKGI
DIRAKVEKAMFNLGDEWRHRDFEGMGKGKDRLKLMMSESSKCIKCYACVE
ACPICYCIECSTKKPWYIAPGVLPTSFMFHLIRFAHVSDSCINCGQCEEL
CPMEIPNALFMHSQQVEIEKMFGHIPGQDMTPPIHAFVEEKAERARLDAT
GTDSIYTNIFT
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7bkc Chain E Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7bkc Three-megadalton complex of methanogenic electron-bifurcating and CO 2 -fixing enzymes.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		C303 P304 C342 I343 N344 C345 G346 C348 M362
Binding residue
(residue number reindexed from 1)		C302 P303 C341 I342 N343 C344 G345 C347 M361
Annotation score4
Enzymatic activity
Enzyme Commision number 1.2.99.-
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0051536 iron-sulfur cluster binding
GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor

View graph for
Molecular Function
External links
PDB RCSB:7bkc, PDBe:7bkc, PDBj:7bkc
PDBsum7bkc
PubMed34516836
UniProtQ2FME3

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