Structure of PDB 6xf9 Chain E Binding Site BS03

Receptor Information
>6xf9 Chain E (length=425) Species: 435895 (Human herpesvirus 8 type M) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVPWQLGTITRHRDELQKLLAASLLPEHPEESLGNPIMTQIHQSLQPSSP
CRVCQLLFSLVRPMGFFEDYACLCFFCLYAPHCWTSTMAAAADLCEIMHL
HFPEEEATYGLFGPGRLMGIDLQLHFFVQKCFKTTAAEKILGISNLQFLK
SEFIRGMLTGTITFKTSWTPCCQITDTTTAPASGIPELARATFCGASRPT
KPSLLPALIDIWSTSSELLDPFFSPPLQADTSQGPCLMHPTLGLRYKNGT
ASVCLLCECLAAHPEAPKALQTLQCEVMGHIENNVKLVDRIAFVLDNPFA
MPYVSDPLLRELIRGCTPQEIHKHLFCDPLCALNAKVVSEDVLFRLPREQ
EYKKLRASAAAGQLLDANTLFDCEVVQTLVFLFKGLQNARVGKTTSLDII
RELTAQLKRHRLDLAHPSQTSHLYA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6xf9 Chain E Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xf9 A pentameric protein ring with novel architecture is required for herpesviral packaging.
Resolution2.22 Å
Binding residue
(original residue number in PDB)		C191 C192 C415 H452
Binding residue
(residue number reindexed from 1)		C171 C172 C373 H410
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:6xf9, PDBe:6xf9, PDBj:6xf9
PDBsum6xf9
PubMed33554858
UniProtP88958

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