Structure of PDB 5jji Chain E Binding Site BS03

Receptor Information

>5jji Chain E (length=400) Species: 83334 (Escherichia coli O157:H7)

NLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEIFGDGVLEILQ
DGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRYFALLKV
NEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLAS
PIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEV
TEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDS
ITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTII
ATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTR
KEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDDFFEMM

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 5jji Chain E Residue 1002

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5jji Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
• Resolution: 2.601 Å
• Binding residue (original residue number in PDB): P180 K184 R212
• Binding residue (residue number reindexed from 1): P164 K168 R196
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:5jji, PDBe:5jji, PDBj:5jji
• PDBsum: 5jji
• PubMed: 27856760
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)