Structure of PDB 4p0s Chain E Binding Site BS03

Receptor Information
>4p0s Chain E (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQQPLELRPGEYRVLLCVDIGETRGPELLRELQRLHVTHTVRKLHVGDFV
WVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKRC
GLERRVYLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESA
AYLALLTRGLQRLYQGHTLRSRPWGTPGPNPLCSLLTFSDFNAGAREVFA
RQLMQVRGVSGEKAAALVDRYSTPASLLAAYDACATPKEQETLLSTIKCG
RLQRNLGPALSRTLSQLYCSYGPLT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4p0s Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substrates.
Resolution6.0 Å
Binding residue
(original residue number in PDB)		E351 Q352 R355
Binding residue
(residue number reindexed from 1)		E92 Q93 R96
Enzymatic activity
Enzyme Commision number 3.1.22.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity
Biological Process
GO:0006302 double-strand break repair
GO:0006308 DNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4p0s, PDBe:4p0s, PDBj:4p0s
PDBsum4p0s
PubMed24733841
UniProtQ96NY9|MUS81_HUMAN Crossover junction endonuclease MUS81 (Gene Name=MUS81)

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