Structure of PDB 4j9u Chain E Binding Site BS03

Receptor Information
>4j9u Chain E (length=451) Species: 223926 (Vibrio parahaemolyticus RIMD 2210633) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIIILGAGQVGGTLAENLVGENNDITIVDNNADRLRELQDKYDLRVVNG
HASHPDVLHEAGAQDADMLVAVTNTDETNMAACQVAFTLFNTPNRVARIR
SPEYLAEKEALFKSGAIPVDHLIAPEELVTSYIERLIQYPGALQVVSFAE
QKVSLVAVKAYGPLVGNALSALREHDTRVAAIFRQGRPIRPQGTTIIEAD
DEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGGGNIGASLAKRLEQTYS
VKLIERDYQRAEKLSEQLENTIVFCGDAADQELLTEENIDQVDVFIALTN
EDETNIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGVIDVAISPQQATIS
ALLTHVRRADIVNVSSLRRGAAEAIEAVAHGDETTSKVVGRAIGDIKLPP
GTTIGAVVRGEEVLIAHDRTVIEQDDHVVMFLVDKKYVPDVEALFQPSPF
F
Ligand information
Ligand IDTBR
InChIInChI=1S/12BrH.6Ta/h12*1H;;;;;;/q;;;;;;;;;;;;;;;;;+1/p-1
InChIKeyYWYIQTPPCOBSGN-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0Br[Ta]123456Br[Ta]17891%10[Ta]22%11(Br7)[Ta]337%12%13([Ta]484([Ta]923(Br%11)(Br1)(Br4)(Br7)Br%12)(Br5)(Br%10)Br%13)Br6
CACTVS 3.370Br|1[Ta]|2|3|4|5|Br[Ta]|6|7|89%10|2|Br[Ta]|%11|%12|%13|%14|1|3|6Br|[Ta]|%15|%16|%17|7|%11(Br|[Ta]|%18|4|%12|%15(Br|%13)(Br|%14)|Br[Ta]|5|8|%16|%18(|Br9)(Br)Br|%17)|Br%10
FormulaBr12 Ta6
NameHEXATANTALUM DODECABROMIDE;
DODECABROMOHEXATANTALUM
ChEMBL
DrugBankDB04119
ZINC
PDB chain4j9u Chain E Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4j9u Gating of the TrkH ion channel by its associated RCK protein TrkA.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		G13 T14 E17 E38 Y43 R332
Binding residue
(residue number reindexed from 1)		G13 T14 E17 E38 Y43 R326
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015079 potassium ion transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006813 potassium ion transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4j9u, PDBe:4j9u, PDBj:4j9u
PDBsum4j9u
PubMed23598339
UniProtQ87KD2

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