Structure of PDB 1ddo Chain E Binding Site BS03
Receptor Information
>1ddo Chain E (length=339) Species:
9823
(Sus scrofa) [
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MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAG
LWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFRE
AVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTE
RLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRG
QIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEI
NNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNL
Ligand information
Ligand ID
DTR
InChI
InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m1/s1
InChIKey
QIVBCDIJIAJPQS-SECBINFHSA-N
SMILES
Software
SMILES
ACDLabs 10.04
O=C(O)C(N)Cc2c1ccccc1nc2
OpenEye OEToolkits 1.5.0
c1ccc2c(c1)c(c[nH]2)CC(C(=O)O)N
CACTVS 3.341
N[CH](Cc1c[nH]c2ccccc12)C(O)=O
CACTVS 3.341
N[C@H](Cc1c[nH]c2ccccc12)C(O)=O
OpenEye OEToolkits 1.5.0
c1ccc2c(c1)c(c[nH]2)C[C@H](C(=O)O)N
Formula
C11 H12 N2 O2
Name
D-TRYPTOPHAN
ChEMBL
CHEMBL292303
DrugBank
DB03225
ZINC
ZINC000000083317
PDB chain
1ddo Chain E Residue 350 [
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Receptor-Ligand Complex Structure
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PDB
1ddo
Active site plasticity in D-amino acid oxidase: a crystallographic analysis.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
R2 D31 K33 G173
Binding residue
(residue number reindexed from 1)
R2 D31 K33 G173
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
L51 G313 T317
Catalytic site (residue number reindexed from 1)
L51 G313 T317
Enzyme Commision number
1.4.3.3
: D-amino-acid oxidase.
Gene Ontology
Molecular Function
GO:0003884
D-amino-acid oxidase activity
GO:0016491
oxidoreductase activity
GO:0071949
FAD binding
Biological Process
GO:0006562
proline catabolic process
GO:0007586
digestion
GO:0019478
D-amino acid catabolic process
GO:0036088
D-serine catabolic process
GO:0042416
dopamine biosynthetic process
GO:0046416
D-amino acid metabolic process
GO:0055130
D-alanine catabolic process
GO:0070945
neutrophil-mediated killing of gram-negative bacterium
Cellular Component
GO:0005576
extracellular region
GO:0005737
cytoplasm
GO:0005777
peroxisome
GO:0005782
peroxisomal matrix
GO:0005829
cytosol
GO:0042995
cell projection
GO:0045202
synapse
GO:0048786
presynaptic active zone
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1ddo
,
PDBe:1ddo
,
PDBj:1ddo
PDBsum
1ddo
PubMed
9153426
UniProt
P00371
|OXDA_PIG D-amino-acid oxidase (Gene Name=DAO)
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