Structure of PDB 7r1o Chain DDD Binding Site BS03

Receptor Information
>7r1o Chain DDD (length=53) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFP
SPF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7r1o Chain DDD Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r1o Dusquetide modulates innate immune response through binding to p62.
Resolution2.202 Å
Binding residue
(original residue number in PDB)		C142 C145 H160 H163
Binding residue
(residue number reindexed from 1)		C23 C26 H41 H44
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7r1o, PDBe:7r1o, PDBj:7r1o
PDBsum7r1o
PubMed35640615
UniProtQ13501|SQSTM_HUMAN Sequestosome-1 (Gene Name=SQSTM1)

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