Structure of PDB 8u98 Chain D Binding Site BS03

Receptor Information
>8u98 Chain D (length=391) Species: 1028307 (Klebsiella aerogenes KCTC 2190) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLDTALVNAGRRKKYTQGSVNSVIQRASSLVFDTVEAKKHATRNRAKGEL
FYGRRGTLTHFSLQEAMCELEGGAGCALFPCGAAAVANTILAFVEQGDHV
LMTNTAYEPSQDFCTKILAKLGVTTGWFDPLIGADIANLIQPNTKVVFLE
SPGSITMEVHDVPAIVAAVRRVAPEAIIMIDNTWAAGVLFKALDFGIDIS
IQAATKYLIGHSDGMIGTAVANARCWEQLCENAYLMGQMIDADTAYMTSR
GLRTLGVRLRQHHESSLRVAEWLAQHPQVARVNHPALPGSKGHEFWKRDF
SGSSGLFSFVLNKRLTDAELAAYLDNFSLFSMAYSWGGFESLILANQPEH
IAAIRPEAEVDFSGTLIRLHIGLENVDDLLADLAAGFARIV
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain8u98 Chain D Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8u98 Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Glycine adduct)
Resolution1.4 Å
Binding residue
(original residue number in PDB)		Y111 K210 Y338 S339 W340 R372
Binding residue
(residue number reindexed from 1)		Y107 K206 Y334 S335 W336 R368
Annotation score1
Enzymatic activity
Enzyme Commision number 4.4.1.8: Transferred entry: 4.4.1.13.
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0046872 metal ion binding
GO:0047804 cysteine-S-conjugate beta-lyase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0019346 transsulfuration
GO:0019450 L-cysteine catabolic process to pyruvate

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8u98, PDBe:8u98, PDBj:8u98
PDBsum8u98
PubMed
UniProtA0A0H3FMF8

[Back to BioLiP]