Structure of PDB 7ye1 Chain D Binding Site BS03

Receptor Information
>7ye1 Chain D (length=1144) Species: 565050 (Caulobacter vibrioides NA1000) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFDQIRISLASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPT
KDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIW
FLKSLPSRIAMMLDMPLKDIERVLYFEYYIVTEPGLTPLKQHQLLSEDDY
MRAQEEYGDDSFTAEIGAEAIQNLLKAIDLEKEAERLREELSGTVSDMKQ
KKFSKRLKILEAFQESGNRPEWMVLTVVPVIPPELRPLVPLDGGRFATSD
LNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGR
VITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLH
ECGLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPQVWDILEE
VIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGD
QMAVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLS
VARDGEPGEGKIFADLGEIEAAMDAGVVSLHAKIKARHTEMTPEGVLLRK
VIDTTPGRMKIAALLPHHPQIGHRLIEKALTKKEIGNLIDIVYRHCGQKA
TVIFADKVMGLGFKEAAKAGISFGKDDIIIPVRKTAIVEETRKLAEEYEQ
QYITKGEKYNKVVDAWAKATDRVADEMMAELQMKHKDENGREKEINAIYM
MAHSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIVSNFKEGLTVQEYFN
STHGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEEDCGTTKGITLRA
VVEGGDVLVSLGSRVLGRFTAEDVKDPGTGELVVPADTYIDENIADAIEA
AVVQSVKVRSVLTCEAKIGVCGACYGRDLARGTPVNIGEAVGVIAAQSIG
EPGTQLTTGGLPRVAELFEARRPKDCAVIAEMDGRVEFGKDYKNKRRIKI
TPDKHIAVHDGDYITKGEYIIDGNPDPHDILRILGVEALANFLVDEIQEV
YRLQGVPINDKHIETIVRQMLQKVEILEPGDTGLIKGDHLDKPEFDKEQE
KAIARGGRPAVTQPVLLGITKASLQTKSFISAASFQETTRVLTEASVHGK
TDTLEGLKENVIVGRLIPAGTGSYLRSLQRVAAKRDEQLAQQRE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7ye1 Chain D Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ye1 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA
Resolution3.7 Å
Binding residue
(original residue number in PDB)		D462 D464 D466
Binding residue
(residue number reindexed from 1)		D446 D448 D450
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ye1, PDBe:7ye1, PDBj:7ye1
PDBsum7ye1
PubMed
UniProtA0A0H3C4W8

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