Structure of PDB 7wae Chain D Binding Site BS03

Receptor Information
>7wae Chain D (length=724) Species: 203124 (Trichodesmium erythraeum IMS101) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKILKLQTLRGPNYWSIHRHKLVVMRLDLEDLYEKYTSDIPGFYKGLTEV
LPSLVEHLCSPGVKGGFLTRVEKGTLIGHVIEHVAIELQELAGMPVGFGR
TRETSTTGVFQVVIEYENEQAGRYAARAAVRLCQSIVDTGTYPATELQQD
LEDLKELKNQASLGPSTEAIVKEAEARGIPWTQLGARFMIQFGYGVNQKK
IQATLSNQTGILGVELACDKEGTKRILKDAGVPVPRGTVARYFDELQDAI
EYVGGYPIVIKPLDGNHGRGITIDVKNWQEAEEAYDLARKASKTKTVIVE
RYYTGKDHRVLVVNGKVVAVAERVPAHVVGNGKSTIAELIEETNRDPQRG
DGHDNILTRITVDKSALDILGKQGYSIDSIPLKGKKCFLRATANLSTGGI
AVDRTDEIHPENVWLLSRVAKIIGLDIAGIDVVTEDISQPLREVEGVIVE
VNAAPGFRMHVAPSRGLARNVAGAVMDMLFPGSKNGRIPILSVTGTNGKT
TTTRLLAHIIKQTGKVVGYTTTDGTYIGEYLAETGDNTGPQSAHLILSDP
TVEVAVLETARGGILRSGLGFSSCEVGIVLNVTADHLGIGDIDTIEQLAK
LKSVVAESVMPKGYAVLNAEDPLVAAMADRVKGQVAYFSMDPNNELLLRH
TEAGGLAAIYENGYISILKGDWTLRIEKAVNVPITMAGKAPFMIANALAA
CLAVFTQGVKIEHIRKGLSTFVAS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7wae Chain D Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wae Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase.
Resolution2.64 Å
Binding residue
(original residue number in PDB)		D431 E450
Binding residue
(residue number reindexed from 1)		D431 E450
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.2.29: cyanophycin synthase (L-aspartate-adding).
6.3.2.30: cyanophycin synthase (L-arginine-adding).
Gene Ontology
Molecular Function
GO:0004326 tetrahydrofolylpolyglutamate synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
GO:0046872 metal ion binding
GO:0071160 cyanophycin synthetase activity (L-aspartate-adding)
GO:0071161 cyanophycin synthetase activity (L-arginine-adding)
Biological Process
GO:0009058 biosynthetic process
GO:0009059 macromolecule biosynthetic process
GO:0009396 folic acid-containing compound biosynthetic process
GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7wae, PDBe:7wae, PDBj:7wae
PDBsum7wae
PubMed36042318
UniProtQ113V7

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