Structure of PDB 6rjn Chain D Binding Site BS03

Receptor Information
>6rjn Chain D (length=502) Species: 4922 (Komagataella pastoris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPPKWTTSNGAPVSDVFATERATFDNANHANNAPKVGPLLLQDFQLIDSL
AHFDRERIPERVVHAKGAGAFGEFEVTDDISDVCAAKFLDTIGKKTRIFT
RFSTVGGEKGSADSARDPRGFSTKFYTEEGNLDLVYNNTPIFFIRDPSKF
PHFIHTQKRNPATNLKDANMFWDYLVNNQESIHQVMYLFSDRGTPASLRK
MNGYSGHTYKWYNKKGEWVYVQVHFKSDLGVVNFNNEEAGKLAGEDPDYH
TGDLFNAIERGEYPSWTCYIQTMTQEQAAKQPFSVFDLTKVWPHKDFPLR
RFGKFTLNENPKNYFAEVEQAAFSPSHTIPSMQPSADPVLQSRLFSYPDT
HRHRLGVNYQQIPVNCPVAPVFTPQMRDGSMTVNGNLGSTPNYKSSFCPF
STEAQIQTNSHTPEEVLAAHTEKFHWGGILDSKSYDFEQPRALWKVFGKT
PGQQRNFCHNVAVHVAAANHEIQDRVFEYFSKVYPEIGDQIRKEVLQLSP
RG
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain6rjn Chain D Residue 609 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6rjn Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes.
Resolution2.295 Å
Binding residue
(original residue number in PDB)		N28 N34 A35 P36 K37
Binding residue
(residue number reindexed from 1)		N26 N32 A33 P34 K35
Annotation score1
Enzymatic activity
Enzyme Commision number 1.11.1.6: catalase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6rjn, PDBe:6rjn, PDBj:6rjn
PDBsum6rjn
PubMed31238127
UniProtC1PHG1

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