Structure of PDB 6n7s Chain D Binding Site BS03

Receptor Information
>6n7s Chain D (length=271) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DGVVSALSLRERIREHLSVGLLFSGCTGINDKTLGARGGEVIMVTSGSGM
GKSTFVRQQALQWGTAMGKKVGLAMLQESVEETAEDLIGLHNRVRLRQSD
SLKREIIENGKFDQWFDELFGNDTFHLYDSTDRLLAKLAYMRSGLGCDVI
ILDHISIVVSRKMIDNLMTKLKGFAKSTGVVLVVICHLKNPDKGKAHEEG
RPVSITDLRGSGALRQLSDTIIALERNQQGDMPNLVLVRILKCRFTGDTG
IAGYMEYNKETGWLEPSSYSG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6n7s Chain D Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6n7s Structures and operating principles of the replisome.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		S319 Q343
Binding residue
(residue number reindexed from 1)		S53 Q77
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
GO:0039693 viral DNA genome replication
Cellular Component
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6n7s, PDBe:6n7s, PDBj:6n7s
PDBsum6n7s
PubMed30679383
UniProtP03692|HELIC_BPT7 DNA helicase/primase (Gene Name=4)

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