Structure of PDB 6hb4 Chain D Binding Site BS03
Receptor Information
>6hb4 Chain D (length=194) Species:
9606
(Homo sapiens) [
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SVLASCPKKPVSSYLRFSKEQLPIFKAQNPDAKTTELIRRIAQRWRELPD
SKKKIYQDAYRAEWQVYKEEISRFKEQLTPSQIMSLEKEIMDKHLKRKAM
TKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQEKLKTVKENWKNLS
DSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKK
Ligand information
>6hb4 Chain F (length=22) [
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taacaattgaatgtctgcacag
Receptor-Ligand Complex Structure
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PDB
6hb4
DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region.
Resolution
3.05 Å
Binding residue
(original residue number in PDB)
Y57 T78 I81 R82 A85 W88 R89 R140 K156 R157 R159 N163 V166 A167 F170 P178
Binding residue
(residue number reindexed from 1)
Y14 T35 I38 R39 A42 W45 R46 R97 K113 R114 R116 N120 V123 A124 F127 P135
Binding affinity
PDBbind-CN
: Kd=4.4nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6hb4
,
PDBe:6hb4
,
PDBj:6hb4
PDBsum
6hb4
PubMed
31114891
UniProt
Q00059
|TFAM_HUMAN Transcription factor A, mitochondrial (Gene Name=TFAM)
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