Structure of PDB 5w7b Chain D Binding Site BS03

Receptor Information
>5w7b Chain D (length=412) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CSLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDS
DKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIIL
LGDAAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLD
SENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPA
IVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHV
ILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWM
SANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQ
KMGGQPWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNP
QIEEVFGDQGGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5w7b Chain D Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w7b Crystal structure of the mammalian lipopolysaccharide detoxifier.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D222 D226 N228 N230 I232 E244
Binding residue
(residue number reindexed from 1)		D64 D68 N70 N72 I74 E86
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w7b, PDBe:5w7b, PDBj:5w7b
PDBsum5w7b
PubMed29343645
UniProtO18823|AOAH_RABIT Acyloxyacyl hydrolase (Gene Name=AOAH)

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