Structure of PDB 5t00 Chain D Binding Site BS03

Receptor Information
>5t00 Chain D (length=143) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHIR
SHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSGT
MKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5t00 Chain D Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t00 Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Resolution2.19 Å
Binding residue
(original residue number in PDB)		C324 C327 H340 H345
Binding residue
(residue number reindexed from 1)		C3 C6 H19 H24
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5t00, PDBe:5t00, PDBj:5t00
PDBsum5t00
PubMed28529057
UniProtP49711|CTCF_HUMAN Transcriptional repressor CTCF (Gene Name=CTCF)

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