Structure of PDB 5kj4 Chain D Binding Site BS03

Receptor Information
>5kj4 Chain D (length=222) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVD
DVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSS
SATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIV
YSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLAN
LRVPSKSNTAKVYIEIQDENDH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5kj4 Chain D Residue 2003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5kj4 An elastic element in the protocadherin-15 tip link of the inner ear.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		E1026 D1075 E1077 D1118
Binding residue
(residue number reindexed from 1)		E129 D178 E180 D221
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kj4, PDBe:5kj4, PDBj:5kj4
PDBsum5kj4
PubMed27857071
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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