Structure of PDB 4l2d Chain D Binding Site BS03

Receptor Information
>4l2d Chain D (length=192) Species: 228 (Pseudoalteromonas haloplanktis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFELPSLPYAIDALEPHISKETLEFHHGKHHNTYVVKLNGLIPGTKFENK
SLEEIVCSSDGGVFNNAAQIWNHTFYWNSLSPNGGGAPTGAVADAINAKW
GSFDAFKEALNDKAVNNFGSSWTWLVKLADGSLDIVNTSNAATPLTDDGV
TPILTVDLWEHAYYIDYRNVRPDYLKGFWSLVNWEFANANFA
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain4l2d Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4l2d Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability.
Resolution2.07 Å
Binding residue
(original residue number in PDB)		H26 H73 D157 H161
Binding residue
(residue number reindexed from 1)		H26 H73 D157 H161
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4l2d, PDBe:4l2d, PDBj:4l2d
PDBsum4l2d
PubMed24440460
UniProtP84612|SODF_PSET1 Superoxide dismutase [Fe] (Gene Name=sodB)

[Back to BioLiP]