Structure of PDB 4hlq Chain D Binding Site BS03

Receptor Information
>4hlq Chain D (length=170) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELD
GKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWL
QEIDRYASENVNKLLVGNKSDLTTKKVVDNTTAKEFADSLGIPFLETSAK
NATNVEQAFMTMAAEIKKRM
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain4hlq Chain D Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4hlq Catalytic mechanism of a mammalian Rab-RabGAP complex in atomic detail.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		S17 K21 S22 T40 G66
Binding residue
(residue number reindexed from 1)		S14 K18 S19 T37 G63
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) Q67
Catalytic site (residue number reindexed from 1) Q64
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4hlq, PDBe:4hlq, PDBj:4hlq
PDBsum4hlq
PubMed23236136
UniProtQ9H0U4|RAB1B_HUMAN Ras-related protein Rab-1B (Gene Name=RAB1B)

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