Structure of PDB 4b2o Chain D Binding Site BS03

Receptor Information

>4b2o Chain D (length=264) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRILFIGDVVGSPGRDMVKEYVPKLKTKYKPHFTIINGENAAHGKGLTEK
IYHSLIQSGADAITMGNHTWDKKEIFDFIDDVPNLVRPANFPEGTPGKGI
TYVKANGKELAVINLQGRTFLPPLDDPFLKADELIAEAAKRTPYIFIDFH
AEATSEKLALGWYTDGRASAVVGTHTHVQTADNRILPKGTAYITDVGMTG
PYDGILGMDRETIIKRFKTNLPVRFTVAEGKTTLSGVVIDIDDQTKKAVK
IERILINDDHMFFE

Ligand information

InChI=1S/Fe/q+2

CWYNVVGOOAEACU-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Fe+2]
CACTVS 3.341	[Fe++]

Formula

Name

FE (II) ION

PDB chain

4b2o Chain D Residue 1267 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4b2o The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis.
Resolution	1.64 Å
Binding residue (original residue number in PDB)	D8 E39 N40 H177
Binding residue (residue number reindexed from 1)	D8 E39 N40 H177
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.4.16: 2',3'-cyclic-nucleotide 2'-phosphodiesterase.

Gene Ontology

	Molecular Function
GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4b2o, PDBe:4b2o, PDBj:4b2o
PDBsum	4b2o
PubMed	24163345
UniProt	O31775\|YMDB_BACSU 2',3'-cyclic-nucleotide 2'-phosphodiesterase (Gene Name=ymdB)

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