Structure of PDB 3wry Chain D Binding Site BS03

Receptor Information
>3wry Chain D (length=432) Species: 12252 (Tobacco mosaic virus strain tomato/L) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLEQFHMATASSLIHKQMCSIVYTGPLKVQQMKNFIDSLVASLSAAVSNL
VKILKLETRQKFGVLDVASKRWLVKPSAKNHAWGVVETHARKYHVALLEH
DEFGIITCDNWRRVAVSSESVVYSDMAKLRTLRRLLKDGEPHVSSAKVVL
VDGVPGCGKTKEILSRVNFEEDLILVPGRQAAEMIRRRANASGIIVATKD
NVRTVDSFLMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEMSLCDIAYV
YGDTQQIPYINRVTGFPYPAHFAKLEVDEVETRRTTLRCPADVTHFLNQR
YEGHVMCTSSEKKSVSQEMVSGAASINPVSKPLKGKILTFTQSDKEALLS
RGYADVHTVHEVQGETYADVSLVRLTPTPVSIIARDSPHVLVSLSRHTKS
LKYYTVVMDPLVSIIRDLERVSSYLLDMYKVD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3wry Chain D Residue 1203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3wry Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1
Resolution2.3 Å
Binding residue
(original residue number in PDB)		N978 Y981 G983
Binding residue
(residue number reindexed from 1)		N298 Y301 G303
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.7.7.-
2.7.7.48: RNA-directed RNA polymerase.
3.6.4.13: RNA helicase.
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3wry, PDBe:3wry, PDBj:3wry
PDBsum3wry
PubMed25092327
UniProtP03587|RDRP_TOML Replicase large subunit

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