Structure of PDB 3v9x Chain D Binding Site BS03

Receptor Information
>3v9x Chain D (length=204) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTL
HFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIK
ASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLA
LGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWP
LSAA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3v9x Chain D Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3v9x How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D23 E25 H181 D186
Binding residue
(residue number reindexed from 1)		D15 E17 H173 D178
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
Gene Ontology
Molecular Function
GO:0000175 3'-5'-RNA exonuclease activity
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006396 RNA processing
GO:0006974 DNA damage response
GO:0008033 tRNA processing
GO:0031125 rRNA 3'-end processing
GO:0034644 cellular response to UV
GO:0042780 tRNA 3'-end processing
GO:0043628 regulatory ncRNA 3'-end processing
GO:0045004 DNA replication proofreading
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3v9x, PDBe:3v9x, PDBj:3v9x
PDBsum3v9x
PubMed22718982
UniProtP30014|RNT_ECOLI Ribonuclease T (Gene Name=rnt)

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