Structure of PDB 3ukm Chain D Binding Site BS03

Receptor Information
>3ukm Chain D (length=252) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSATMFGFLVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEH
ECLSEQQLEQFLGRVLEASNYGVSVLWNWDFTSALFFASTVLSTTGYGHT
VPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTRRPVLYFSKQVV
AIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLG
DYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKKFRKM
FY
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain3ukm Chain C Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ukm Crystal structure of the human two-pore domain potassium channel K2P1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T117 T118 T225 I226
Binding residue
(residue number reindexed from 1)		T94 T95 T196 I197
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ukm, PDBe:3ukm, PDBj:3ukm
PDBsum3ukm
PubMed22282804
UniProtO00180|KCNK1_HUMAN Potassium channel subfamily K member 1 (Gene Name=KCNK1)

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