Structure of PDB 3j5s Chain D Binding Site BS03

Receptor Information
>3j5s Chain D (length=554) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAGKSTLLRI
MAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNAL
KRLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADAL
RLPDWDAKIANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWL
ERFLHDFEGTVVAITHDRYFLDNVAGWILELDRGEGIPWEGNYSSWLEQK
DQRLAQEASQEAARRKSIEKELEWVRQGTKGRQSKGKARLARFEELNSTE
YQKRNETNELFIPPGPRLGDKVLEVSNLRKSYGDRLLIDDLSFSIPKGAI
VGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVDQFRDSMDNS
KTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGERG
RLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDR
WFLDRIATHILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYK
RIAK
Ligand information
>3j5s Chain E (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB3j5s EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics.
Resolution7.5 Å
Binding residue
(original residue number in PDB)		R277 Q278
Binding residue
(residue number reindexed from 1)		R276 Q277
Enzymatic activity
Enzyme Commision number 3.6.1.-
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0019843 rRNA binding
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006417 regulation of translation
GO:0045900 negative regulation of translational elongation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3j5s, PDBe:3j5s, PDBj:3j5s
PDBsum3j5s
PubMed24389465
UniProtP0A9W3|ETTA_ECOLI Energy-dependent translational throttle protein EttA (Gene Name=ettA)

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