Structure of PDB 3h9q Chain D Binding Site BS03

Receptor Information

>3h9q Chain D (length=333) Species: 562 (Escherichia coli)

MDYILGRYVKIARYGSGGLVGGGGKEQYVENLVLWENIIKTAYCFITPSS
YTAALETANIPEKDFSNCFRFLKENFFIIPGEYNNNNRYSRNFLHYQSYG
ANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENT
NLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKV
PEADIWVVSADHPFNLINWVNKYCVRANQPYINAGYVNDIAVFGPLYVPG
KTGCYECKENIDHKIKLINSRFKPATFAPVNNVAAALCAADVIKFIGKYS
EPLSLNKRIGIWSDEIKIHSQNMGRSPVCSVCG

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 3h9q Chain D Residue 500

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3h9q How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
• Resolution: 2.63 Å
• Binding residue (original residue number in PDB): C257 C260 C343
• Binding residue (residue number reindexed from 1): C254 C257 C329
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): R157
• Catalytic site (residue number reindexed from 1): R154

Gene Ontology

Molecular Function

• GO:0004792 thiosulfate sulfurtransferase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008641 ubiquitin-like modifier activating enzyme activity
• GO:0016779 nucleotidyltransferase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3h9q, PDBe:3h9q, PDBj:3h9q
• PDBsum: 3h9q
• PubMed: 19494832
• UniProt: Q47506