Structure of PDB 3gqc Chain D Binding Site BS03

Receptor Information
>3gqc Chain D (length=433) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLQSCIMH
VDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEWQYYQ
NANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFH
AYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPDEFANAV
RMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRGQ
LVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRF
CRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEEIQRRLE
ATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQATDNAK
IIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPT
Ligand information
Receptor-Ligand Complex Structure
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PDB3gqc Structure of the human Rev1-DNA-dNTP ternary complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		F352 Y353 H355 S356 R357 L358 H359 S362 S448 P456 S504 R505 A506 E507 K686 T687 R709 K710 S711 S713 A714 E715 N717 Y718 R742 K770 F771 G773 H774 G775
Binding residue
(residue number reindexed from 1)		F7 Y8 H10 S11 R12 L13 H14 S17 S77 P85 S110 R111 A112 E113 K292 T293 R315 K316 S317 S319 A320 E321 N323 Y324 R348 K376 F377 G379 H380 G381
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3gqc, PDBe:3gqc, PDBj:3gqc
PDBsum3gqc
PubMed19464298
UniProtQ9UBZ9|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)

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