Structure of PDB 2cnw Chain D Binding Site BS03

Receptor Information
>2cnw Chain D (length=281) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AIPWGGNLEEVLEELEMALLAADVGLSATEEILQEVRASGRKDLKEAVKE
KLVGMLEPDERRATLRKLGFQKPKPVEPKGRVVLVVGVNGVGKTTTIAKL
GRYYQNLGKKVMFCAGDTFRAAGGTQLSEWGKRLSIPVIQGPEGTDPAAL
AYDAVQAMKARGYDLLFVDTAGRLHTKHNLMEELKKVKRAIAKADPEEPK
EVWLVLDAVTGQNGLEQAKKFHEAVGLTGVIVTKLDGTAKGGVLIPIVRT
LKVPIKFVGVGEGPDDLQPFDPEAFVEALLE
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain2cnw Chain D Residue 1007 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cnw Structure of a Gdp:Alf(4) Complex of the Srp Gtpases Ffh and Ftsy, and Identification of a Peripheral Nucleotide Interaction Site.
Resolution2.39 Å
Binding residue
(original residue number in PDB)		N111 K115 D139 R142 G194
Binding residue
(residue number reindexed from 1)		N89 K93 D117 R120 G172
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005047 signal recognition particle binding
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006605 protein targeting
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cnw, PDBe:2cnw, PDBj:2cnw
PDBsum2cnw
PubMed16780874
UniProtP83749|FTSY_THEAQ Signal recognition particle receptor FtsY (Gene Name=ftsY)

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