Structure of PDB 1p4e Chain D Binding Site BS03

Receptor Information
>1p4e Chain D (length=409) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQFDILCKTPPKVLVRQFVERFERPSGEKIASCAAELTYLCWMITHNGTA
IKRATFMSYNTIISNSLSFDIVNKSLQFKYKTQKATILEASLKKLIPAWE
FTIIPYNSDITDIVSSLQLQFESSGNSHSKKMLKALLSEGESIWEITEKI
LNSFEYTSRFTKTKTLYQFLFLATFINCGRFSDIKNVDPKSFKLVQNKYL
GVIIQCLVTETKTSVSRHIYFFSARGRIDPLVYLDEFLRNSEPVLKRVNR
TGNSNKQEYQLLKDNLVRSYNKALKKNAPYPIFAIKNGPKSHIGRHLMTS
FLSMKGLTELTNVVGNFSDKRASAVARTTYTHQITAIPDHYFALVSRYYA
YDPISKEMIALKDETNPIEEWQHIEQLKGSAEGSIRYPAWNGIISQEVLD
YLSSYINRR
Ligand information
Ligand ID2PO
InChIInChI=1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3)/p-2
InChIKeyABLZXFCXXLZCGV-UHFFFAOYSA-L
SMILES
SoftwareSMILES
ACDLabs 10.04[O-]P([O-])=O
CACTVS 3.341[O-][PH]([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)[O-]
FormulaH O3 P
NamePHOSPHONATE
ChEMBL
DrugBank
ZINC
PDB chain1p4e Chain H Residue 513 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1p4e The role of the conserved Trp330 in Flp-mediated recombination. Functional and structural analysis
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R191 K223 H305
Binding residue
(residue number reindexed from 1)		R180 K212 H292
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0008301 DNA binding, bending
GO:0009009 site-specific recombinase activity
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration
GO:0042150 plasmid recombination
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1p4e, PDBe:1p4e, PDBj:1p4e
PDBsum1p4e
PubMed12716882
UniProtP03870|FLP_YEAST Site-specific recombinase Flp (Gene Name=FLP1)

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