Structure of PDB 1nfv Chain D Binding Site BS03

Receptor Information
>1nfv Chain D (length=170) Species: 876 (Desulfovibrio desulfuricans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GNREDRKAKVIEVLNKARAMELHAIHQYMNQHYSLDDMDYGELAANMKLI
AIDEMRHAENFAERIKELGGEPTTQKEGKVVTGQAVPVIYESDADQEDAT
IEAYSQFLKVCKEQGDIVTARLFERIIEEEQAHLTYYENIGSHIKNLGDT
YLAKIAGTPSSTGTASKGFV
Ligand information
Ligand ID3PY
InChIInChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)
InChIKeyHHDDCCUIIUWNGJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CO
CACTVS 3.341OCC(=O)C(O)=O
OpenEye OEToolkits 1.5.0C(C(=O)C(=O)O)O
FormulaC3 H4 O4
Name3-HYDROXYPYRUVIC ACID
ChEMBLCHEMBL1230192
DrugBankDB02951
ZINCZINC000001532558
PDB chain1nfv Chain D Residue 1310 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1nfv The nature of the di-iron site in the bacterioferritin from Desulfovibrio desulfuricans
Resolution1.95 Å
Binding residue
(original residue number in PDB)		R127 E131
Binding residue
(residue number reindexed from 1)		R125 E129
Annotation score1
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0034755 iron ion transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:1nfv, PDBe:1nfv, PDBj:1nfv
PDBsum1nfv
PubMed12627224
UniProtQ93PP9|BFR_DESDA Bacterioferritin (Gene Name=bfr)

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