Structure of PDB 4v8z Chain CV Binding Site BS03

Receptor Information
>4v8z Chain CV (length=568) Species: 187420,559292 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDLRSPICCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPID
AIKAKTKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILV
IDIMHGLEQQTIESIKLLRDRKAPFVVALNKIDRLYDWKAIPNNSFRDSF
AKQSRAVQEEFQSRYSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAV
TGEGVPDLLWLLLELTQKRMSKQLMYLSHVEATILEVKVVEGFGTTIDVI
LSNGYLREGDRIVLCGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVK
AALGVKIAANDLEKAVSGSRLLVVGPEDDEDELMDDVMDAGVVVKADTLG
SLEAVVKILRDMYVPIKVADIGDVSRRDVVNAGIALQEDRVYGAIIAFNV
KVIPSAAQELKNSDIKLFQGNVIYRLMEEYEEWVRGIEEEKKKKWMEAII
KPASIRLIPKLVFRQSKPAIGGVEVLTGVIRQGYPLMNDDGETVGTVESM
QDKGENLKSASRGQKVAMAIKDAVYGKTIHEGDTLYVDIPENHYHILLTD
EELDLMDKIAEIKRKKNP
Ligand information
>4v8z Chain CW (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcccggauagcucagucgguagagcaggggauucauaauccccguguccu
ugguucgauuccgaguccgggcacca
....<<<..<<<<........>>>>.<<<<<<.....>>>>>>.....<<
<<<.......>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB4v8z Molecular architecture of a eukaryotic translational initiation complex.
Resolution6.6 Å
Binding residue
(original residue number in PDB)		V535 Y536 G537 K538 T539 I540 H541
Binding residue
(residue number reindexed from 1)		V524 Y525 G526 K527 T528 I529 H530
Enzymatic activity
Enzyme Commision number ?
3.6.5.3: protein-synthesizing GTPase.
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:4v8z, PDBe:4v8z, PDBj:4v8z
PDBsum4v8z
PubMed24200810
UniProtO26359|IF2P_METTH Probable translation initiation factor IF-2 (Gene Name=infB);
P39730|IF2P_YEAST Eukaryotic translation initiation factor 5B (Gene Name=FUN12)

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