Structure of PDB 8bqs Chain CB Binding Site BS03

Receptor Information
>8bqs Chain CB (length=285) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AESNDATSICLESISGTIKGLQKANYVVEHNPNLTSEEKKHLKQFLVYRY
NPADPHDQPKYVSYWCDIKKFPPMFLDAILYIKNELDPTLSIRRSCREGI
CGSCAVNCDGLHTLACISGFNRDLSKPTIITPLGHMFILKDLVVDMTNFY
AQYKMIEPYLKRKTPKPDANKEYPQSPEQRALLDGLYECVLCAACSTSCP
SYWWHPDRYLGPAILQQAYRWIVDSRDEYTQERIERIAEDVRLDDCQQIG
MCSFTCPKGLNPQLSLKNLMDMVKDFRQKRIEQEV
Ligand information
Ligand IDF3S
InChIInChI=1S/3Fe.4S
InChIKeyFCXHZBQOKRZXKS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385S1[Fe]S[Fe]2S[Fe]1S2
OpenEye OEToolkits 2.0.7S1[Fe]2S[Fe]3[S]2[Fe]1S3
FormulaFe3 S4
NameFE3-S4 CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8bqs Chain CB Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bqs Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C225 C272 Q273 Q274 I275 G276 C278 Q289 L292
Binding residue
(residue number reindexed from 1)		C199 C246 Q247 Q248 I249 G250 C252 Q263 L266
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0008177 succinate dehydrogenase (quinone) activity
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051538 3 iron, 4 sulfur cluster binding
Biological Process
GO:0006099 tricarboxylic acid cycle
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bqs, PDBe:8bqs, PDBj:8bqs
PDBsum8bqs
PubMed
UniProtI7M403

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