Structure of PDB 8wa0 Chain C Binding Site BS03

Receptor Information
>8wa0 Chain C (length=661) Species: 4097 (Nicotiana tabacum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIDRYKHQQLRIGSVSPQQISAWATKILPNGEIVGEVTKPYTFHYKTNKP
EKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVDSRIR
RYQMGYIKLACPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARP
ITKKPTFLRLRGLFEYEIQSWKYSIPLFFTTQGFDTFRNREISTGAGAIR
EQLADLDLRIIIENSLVEWEELGEEGHTGNEWEDRKVGRRKDFLVRRVEL
AKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVI
YRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHN
KVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPRE
IAIELFQTFVIRGLIRQHLASNIGVAKSKIREKEPIVWEILQEVMQGHPV
LLNRAPTLHRLGIQAFQPVLVEGRAICLHPLVCKGFNADFDGDQMAVHVP
LSLEAQVEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSGNHRGI
CVNRYNPCNRKEPFFSNSYDAIGAYRQKRINLDSPLWLRWRLDQRVIASR
ETPIEVHYESLGTFYEIYGHYLIVRSLKKQILFIYIRTTVGHIALYREIE
EAIQGFSRAYS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8wa0 Chain C Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8wa0 Cryo-EM structures of the plant plastid-encoded RNA polymerase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D496 D498 D500
Binding residue
(residue number reindexed from 1)		D489 D491 D493
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0009507 chloroplast

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8wa0, PDBe:8wa0, PDBj:8wa0
PDBsum8wa0
PubMed38428393
UniProtA0A140G1Q3

[Back to BioLiP]