Structure of PDB 8tit Chain C Binding Site BS03

Receptor Information
>8tit Chain C (length=210) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSDGICEIHVAKYAEIF
GLTSAEASKDIRQALKSFAGKEVVFYYESFPWFIKPAHSPSRGLYSVHIN
PYLIPFFIGRFTQFRLSETKEITNPYAMRLYESLCQYRKPDGSGIVSLKI
DWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGRQT
THIVFSFRDI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8tit Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8tit Towards automated crystallographic structure refinement with phenix.refine.
Resolution2.84 Å
Binding residue
(original residue number in PDB)		E77 D81
Binding residue
(residue number reindexed from 1)		E56 D60
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006276 plasmid maintenance
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8tit, PDBe:8tit, PDBj:8tit
PDBsum8tit
PubMed
UniProtP03856|REPE1_ECOLI Replication initiation protein (Gene Name=repE)

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