Structure of PDB 8ro0 Chain C Binding Site BS03

Receptor Information
>8ro0 Chain C (length=898) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDKKYYATALEVYGEGVETLVQEEDAQPLTEPIVKPVSKKKFQAAERFLP
ETVYKKEYLADLMDCPHIMRNVAIAGHLHHGKTTFLDCLMEQTHPEFYRA
EDADARFTDILFIEKQRGCSIKSQPVSIVAQDSRSKSYLLNIIDTPGHVN
FSDEMTASYRLADGVVVMVDAHEGVMMNTERAIRHAIQERLAVTLCISKI
DRLLLELKLPPADAYFKLRLIIDQVNNILSTFAEEDVPVLSPLNGNVIFS
SGRYNVCFSLLSFSNIYAKQHGDSFNSKEFARRLWGDIYFEKKTRKFVKK
SPSHDAPRTFVQFILEPMYKIFSQVVGDVDTCLPDVMAELGIRLSKEEQK
MNVRPLIALICKRFFGDFSAFVDLVVQNIKSPLENAKTKIEQTYLGPADS
QLAQEMQKCNAEGPLMVHTTKNYPVDDATQFHVFGRVMSGTLEANTDVRV
LGENYSIQDEEDCRRMTVGRLFVRVASYQIEVSRVPAGCWVLIEGIDQPI
VKTATIAELGYEEDVYIFRPLKFNTRSCVKLAVEPINPSELPKMLDGLRK
VNKSYPLLTTRVEESGEHVLLGTGEFYMDCVMHDMRKVFSEIDIKVADPV
VTFNETVIETSTLKCFAETPNKKNKITMMAEPLEKQLDEDIENEVVQIGW
NRRRLGEFFQTKYNWDLLAARSIWAFGPDTTGPNILLDDTLPSEVDKHLL
STVRESLVQGFQWATREGPLCEEPIRQVKFKLLDAAIATEPLYRGGGQMI
PTARRCAYSAFLMATPRLMEPYYTVEVVAPADCVAAVYTVLAKRRGHVTT
DAPMPGSPMYTISAYIPVMDSFGFETDLRIHTQGQAFCMSAFHHWQLVPG
DPLDKSIVIKTLDVQPTPHLAREFMIKTRRRKGLSEDVSVNKFFDDPM
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8ro0 Chain C Residue 1102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ro0 Mechanism for the initiation of spliceosome disassembly.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T146 S183 D207
Binding residue
(residue number reindexed from 1)		T83 S120 D144
Annotation score4
External links