Structure of PDB 8d3p Chain C Binding Site BS03

Receptor Information
>8d3p Chain C (length=343) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKLLNTLYVTQPDTYLSLDGDNVVLLKEQEKLGRLPLHNLEAIVGFGYT
GASPALMGYCAERNISITFLTKNGRFLARVVGESRGNVVLRKTQYRISEN
DQESTKIARNFITGKVYNSKWMLERMTREHPLRVNVEQFKATSQLLSVMM
QEIRNCDSLESLRGWEGQAAINYNKVFDQMILQQKEEFAFHGRSRRPPKD
NVNAMLSFAYTLLANDVAAALETVGLDAYVGFMHQDRPGRASLALDLMEE
LRGLYADRFVLSLINRKEMTADGFYKKENGAVLMTDEARKTFLKAWQTKK
QEKITHPYLGEKMSWGLVPYVQALLLARFLRGDLDEYPPFLWK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d3p PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution4.26 Å
Binding residue
(original residue number in PDB)		E166 A170 N174 R193
Binding residue
(residue number reindexed from 1)		E166 A170 N174 R193
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d3p, PDBe:8d3p, PDBj:8d3p
PDBsum8d3p
PubMed36272411
UniProtQ9KFX9

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