Structure of PDB 8ahx Chain C Binding Site BS03

Receptor Information

>8ahx Chain C (length=476) Species: 322710 (Azotobacter vinelandii DJ)

FNLSSIRGGVHPAAHKDLSAALPIGSLPLPPRLYLPLRQHAGAEALPMVA
VGDKVLKGQLLAFPPTEVSAPVHAPTSGRIVAIGPVPAPHPSGLTTTGIV
LESDGEDRWIDLDVSTDPFAEDPLVLADRVAKAGIVGLGGAIFPAAVKLK
QGTRHEIKTVLVNGSECEPYLTCDDRIMRERAEAIVDGARLIQHILRAYS
VVIAIEDNKPEALAAMRAAAEHFGAIEVMAVPALYPMGSAKQLIQAVTGR
EVPAGGRSTDVGVLVHNAGTVYAIQQALRFGRPLISRVVTVSGACVKTPQ
NLDVLIGTPVQALIDACGGLSGDPQQLLLGGPMMGAVLPSTEVPVIKGAT
GLLALARHELPNKDPAPCIRCASCVDACPMGLTPLDMALYARADDYDGAS
EYGLRDCILCGCCSYVCPSHIPLVHYFQYAKGQQDERRSAARKSDYIKRQ
TEVRAARLAEEEAAKAAAKAAKEAAK

Ligand information

• Ligand ID: SF4
• InChI: InChI=1S/4Fe.4S
• InChIKey: LJBDFODJNLIPKO-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 2.0.7: [S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
  CACTVS 3.385: S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
• Formula: Fe4 S4
• Name: IRON/SULFUR CLUSTER
• PDB chain: 8ahx Chain C Residue 502

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8ahx Architecture of the NADH:ferredoxin oxidoreductase RNF that drives Biological Nitrogen Fixation
• Resolution: 3.11 Å
• Binding residue (original residue number in PDB): C380 P381 C409 I410 L411 C412 G413 C415
• Binding residue (residue number reindexed from 1): C378 P379 C407 I408 L409 C410 G411 C413
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 7.-.-.-

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0022900 electron transport chain

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:8ahx, PDBe:8ahx, PDBj:8ahx
• PDBsum: 8ahx
• PubMed: 38890433
• UniProt: C1DMA6