Structure of PDB 7z03 Chain C Binding Site BS03

Receptor Information
>7z03 Chain C (length=374) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAI
CLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNR
ARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRS
MLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTEL
EQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYL
LQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKER
IPVQIKVKKINGLGYSKLESTFAV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7z03 Chain C Residue 1102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7z03 Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		T44 Q155
Binding residue
(residue number reindexed from 1)		T44 Q155
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008296 3'-5'-DNA exonuclease activity
GO:0016887 ATP hydrolysis activity
GO:1990238 double-stranded DNA endonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
Cellular Component
GO:1990391 DNA repair complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7z03, PDBe:7z03, PDBj:7z03
PDBsum7z03
PubMed35987200
UniProtP13458|SBCC_ECOLI Nuclease SbcCD subunit C (Gene Name=sbcC)

[Back to BioLiP]