Structure of PDB 7xyb Chain C Binding Site BS03

Receptor Information
>7xyb Chain C (length=1190) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKEQFRDVG
LHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRV
KVRLIIFDRESSNKAIKDIKEQEVYMGEIPLMTENGTFIINGTERVIVSQ
LHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRI
DRRRKLPASVLLRALGYSTEEILNAFYATLYTNDIDCGPFISDTLKIDNT
SNQLEALVEIYRMMRPGEPPTKEAAETLFGNLFFSAERYDLSAVGRMKFN
RRIGRTEIEGPGVLSKEDIIDVLKTLVDIRNGKGIVDDIDHLGNRRVRCV
GEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAIKEFF
GSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLATYARTNKYGFLESPYRVVKDSLVTDEIVFL
SAIEEADHVIAQASATLNEKGQLVDELVAVRHLNEFTVKAPEDVTLMDVS
PKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMER
NVARDSGVCVVARRGGVIDSVDASRVVVRVADDEVETGEAGVDIYNLTKY
TRSNQNTCINQRPLVSKGDVVARGDILADGPSTDMGELALGQNMRVAFMP
WNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPN
VGEAALNKLDEAGIVYVGAEVQAGDILVGKVTPVKDTSLRVPTGTKGTVI
DVQVFTRDGVERDSRALSIEKMQLDQIRKDLNEEFRIVEGATFERLRAAL
VGAADDALNEQLEKAQAYISDRRQLLDDKFEDKKRKLQQGDDLAPGVLKI
VKVYLAIKRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDIVLN
PLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRKVAELRKFLHEIY
NEIGGREENLDELGDNEILALAKNLRGGVPMATPVFDGAKEREIKAMLKL
ADLPESGQMRLFDGRTGNQFERPTTVGYMYMLKLNHLVDDKMHARSTGSY
SLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGR
TKMYKNIVDGDHRMEAGMPESFNVLIKEIRSLGIDIELET
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7xyb Structural basis of AlpA-dependent transcription antitermination.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R147 K508 K1277
Binding residue
(residue number reindexed from 1)		R145 K397 K1111
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xyb, PDBe:7xyb, PDBj:7xyb
PDBsum7xyb
PubMed35871295
UniProtQ51561|RPOB_PSEAE DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

[Back to BioLiP]