Structure of PDB 7xvn Chain C Binding Site BS03

Receptor Information
>7xvn Chain C (length=81) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCAYSCTRQQNCPIDRT
SRNRCQHCRLQKCLALGMSRDAVKFGRMSKK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xvn Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xvn Structural basis for DNA recognition feature of retinoid-related orphan receptors
Resolution2.302 Å
Binding residue
(original residue number in PDB)		C31 C34 C48 C51
Binding residue
(residue number reindexed from 1)		C5 C8 C22 C25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7xvn, PDBe:7xvn, PDBj:7xvn
PDBsum7xvn
PubMed38309263
UniProtP51450|RORG_MOUSE Nuclear receptor ROR-gamma (Gene Name=Rorc)

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